Wapello is a city located in Louisa County, in the state of Iowa (IA), United States. Nestled in the West North Central division of the Midwest region, it covers an area of 1.3 square miles (3.0 km²) and sits at an elevation of 580 ft. With a population of approximately 2,124 residents, Wapello offers a peaceful, rural atmosphere.
The town's population is composed of about 48.4% males and 51.6% females, and it has a population density of 685.71 people per square mile (650.86/km²). Wapello lies at a latitude of 41.18 and a longitude of -91.19, operating in the UTC-6.
Locals reflect a blend of American ancestry, with roots primarily in United States (8.7%), followed by English (10.5%), German (29.7%), and Scotch-Irish (0%) heritage. The town is identified by the ZIP code 52653.