Mclain is a town located in Greene County, in the state of Mississippi (MS), United States. Nestled in the East South Central division of the South region, it covers an area of 3.4 square miles (9.0 km²) and sits at an elevation of 77 ft. With a population of approximately 603 residents, Mclain offers a peaceful, rural atmosphere.
The town's population is composed of about 45.77% males and 54.23% females, and it has a population density of 177.88 people per square mile (68.68/km²). Mclain lies at a latitude of 31.1 and a longitude of -88.82, operating in the UTC-6.
Locals reflect a blend of American ancestry, with roots primarily in United States (27.9%), followed by English (6%), German (0%), and Scotch-Irish (2%) heritage. The town is identified by the ZIP code 39456.