Lee County is a county located in the U.S. state of Mississippi. As of the most recent data available, the county has a population of approximately 75,755 people, with a population density of about 168.34 persons per square mile.
The county spans a total land area of 450.00 square miles (1,165.00 square kilometers). The administrative center and county seat is Tupelo, which often serves as a hub for local governance and services. The largest city within the county by population is Tupelo.
Geographically, Lee County experiences varied elevations, with its highest point at Guntown 384 ft and its lowest point at Shannon 265 ft. The region operates in the UTC-6.