Keytesville is a city located in Chariton County, in the state of Missouri (MO), United States. Nestled in the West North Central division of the Midwest region, it covers an area of 0.7 square miles (2.0 km²) and sits at an elevation of 709 ft. With a population of approximately 533 residents, Keytesville offers a peaceful, rural atmosphere.
The town's population is composed of about 46.9% males and 53.1% females, and it has a population density of 761.43 people per square mile (293.99/km²). Keytesville lies at a latitude of 39.43 and a longitude of -92.94, operating in the UTC-6.
Locals reflect a blend of American ancestry, with roots primarily in United States (26.6%), followed by English (6.8%), German (19.7%), and Scotch-Irish (0%) heritage. The town is identified by the ZIP code 65261.