Mississippi County is a county located in the U.S. state of Missouri. As of the most recent data available, the county has a population of approximately 13,427 people, with a population density of about 32.51 persons per square mile.
The county spans a total land area of 413.00 square miles (1,070.00 square kilometers). The administrative center and county seat is Charleston, which often serves as a hub for local governance and services. The largest city within the county by population is Charleston.
Geographically, Mississippi County experiences varied elevations, with its highest point at Bertrand 325 ft and its lowest point at Charleston 0 ft. The region operates in the UTC-6.