Puxico is a city located in Stoddard County, in the state of Missouri (MO), United States. Nestled in the West North Central division of the Midwest region, it covers an area of 0.6 square miles (1.0 km²) and sits at an elevation of 370 ft. With a population of approximately 1,145 residents, Puxico offers a peaceful, rural atmosphere.
The town's population is composed of about 51.79% males and 48.21% females, and it has a population density of 81.82 people per square mile (803.79/km²). Puxico lies at a latitude of 36.95 and a longitude of -90.16, operating in the UTC-6.
Locals reflect a blend of American ancestry, with roots primarily in United States (9.3%), followed by English (8.2%), German (11.4%), and Scotch-Irish (0%) heritage. The town is identified by the ZIP code 63960.