Madison County is a county located in the U.S. state of Missouri. As of the most recent data available, the county has a population of approximately 11,800 people, with a population density of about 23.74 persons per square mile.
The county spans a total land area of 497.00 square miles (1,287.00 square kilometers). The administrative center and county seat is Fredericktown, which often serves as a hub for local governance and services. The largest city within the county by population is Fredericktown.
Geographically, Madison County experiences varied elevations, with its highest point at Junction City 745 ft and its lowest point at Marquand 571 ft. The region operates in the UTC-6.