Fredericktown is a city located in Madison County, in the state of Missouri (MO), United States. Nestled in the West North Central division of the Midwest region, it covers an area of 4.3 square miles (11.0 km²) and sits at an elevation of 743 ft. With a population of approximately 3,928 residents, Fredericktown offers a peaceful, rural atmosphere.
The town's population is composed of about 43.84% males and 56.16% females, and it has a population density of 919.91 people per square mile (355.18/km²). Fredericktown lies at a latitude of 37.56 and a longitude of -90.29, operating in the UTC-6.
Locals reflect a blend of American ancestry, with roots primarily in United States (19.3%), followed by English (7.4%), German (16.4%), and Scotch-Irish (0%) heritage. The town is identified by the ZIP code 63645.